People are
more likely to catch the common gut bug, C. difficile, after a course
of antibiotics—but now researchers think that standard painkillers pose a
similar risk.
The
NSAID (non-steroidal, anti-inflammatory drugs) painkillers make
Clostridium difficile infection more likely, and worsen the symptoms,
which can include diarrhea, stomach pains and fatigue; it's also one of
the most dangerous infections caught in hospitals and care homes, with
the US's Centers for Disease Control and Prevention (CDC) estimating
that 15,000 Americans die each year as a direct result of infection.
It's known that people are more susceptible to the bug after a course of antibiotics that can disturb the bacteria in the gut, but researchers from the University of Michigan say that NSAIDs pose a similar risk.
Their fears are based on tests on laboratory mice, some of whom were given an NSAID. Just 20 per cent of those given a painkiller survived the infection, whereas 80 per cent of those not given the drug did so.
It's known that people are more susceptible to the bug after a course of antibiotics that can disturb the bacteria in the gut, but researchers from the University of Michigan say that NSAIDs pose a similar risk.
Their fears are based on tests on laboratory mice, some of whom were given an NSAID. Just 20 per cent of those given a painkiller survived the infection, whereas 80 per cent of those not given the drug did so.
References
(Source: mBio, 2019; 10: doi: 10.1128/mBio.02282-18)Click Here For More Articles
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