Showing posts with label blood flow. Show all posts
Showing posts with label blood flow. Show all posts

Thursday, 23 April 2015

Wheat and Mental Health: Does Gluten Affect Blood Flow To The Brain?

Mr-grain_brain_blood_flow

The use of gluten is universal. This common protein is found in most of the world’s grains including wheat, barley and spelt, and it is almost always a prime ingredient in the production of breads, processed foods, pastas, rolls and crusts. As is the way of that old expression, “one man’s meat is another’s poison”, gluten can and often does cause serious health problems, the most prominently studied of which is Celiac Disease. According to the New England Journal of Medicine, more than 50 ailments are either caused or intensified by the ingestion of gluten, including anxiety and depression.
It was first suspected that wheat consumption cuts off the blood flow to the brain back in 1954 when the disappearance of symptoms considered part of the schizophrenia syndrome in patients consuming gluten free diets first appeared in medical literature.

In 1966, F.C. Dohan, M.D. conducted a remarkable study involving women in Finland, Norway, Sweden, Canada and the United States before and after World War II, the purpose of which was to confirm the possible connection between schizophrenia and celiac disease. Findings were published in The American Journal of Clinical Nutrition. It was called: Wheat “Consumption and Hospital Admissions for Schizophrenia During World War II.

The most outstanding study dates back to a 1987 case study involving a 33-year-old patient that was published in the Journal of Internal Medicine. This patient had a pre-existing diagnosis of schizophrenia, which was accompanied by classic signs of gluten intolerance; severe diarrhea and weight loss. Thanks to brain scan technology, doctors discovered a decreased blood flow to the brain within the patient’s frontal cortex. Blood flow returned to the area and the diagnosis completely changed after a gluten-free diet was implemented.

Dr. David Perlmutter’s best selling book on the subject, Grain Brain, has opened the eyes of the world to the fact that grains can and do negatively affect brain health. The disruption of blood flow to the frontal cortex profoundly concerns mankind, for it is this area of the brain that controls choosing between “good” and “bad” actions, suppressing socially unaccepted behavior, long-term memory and the recognition of consequences resulting from current actions.

Two other important studies researched the gluten-gut-brain connection. The first, “Association Between Headache and Sensitivities to Gluten and Dairy, was published in the Journal of Integrative Medicine. The second study, Overlapping with Crohn’s Disease: A Case Series, appeared in Case Reports in Immunology and addressed what appeared to be three different diagnoses gluten sensitivity.

In conclusion, studies on gluten, while remarkable, are not yet conclusive. It does seem clear, however that mood disorders related to gluten sensitivity have been considerably under-diagnosed. Hopefully, ongoing research will eventually unravel the entire truth concerning its ramifications. It can be assumed however, that if the consumption of wheat interferes with blood flow to the brain in even some individuals, abstaining from it can be the best solution.

Wednesday, 23 July 2014

Is Laughter the Best Medicine?

There's some scientific evidence that "Take two jokes and call me in the morning" is a worthwhile prescription. But not much.

By Susan Brink

We all want to believe that laughter is good for what ails us, but the science backing that up is thin. Most studies have been small and have relied on self-reported assessments.





Still, a rollicking good guffaw can't hurt. Or can it? There are rare instances of laughter prompting an asthma attack and even rarer instances of it triggering a stroke. And though this hasn't been part of a formal study, one researcher speculates that if you're surrounded by people laughing inappropriately—finding, say, a cockfight hilarious—it increases stress.
However, a few studies relying on laboratory testing do show some benefits.
"A good belly laugh leads to the release of endorphins from the brain," says Michael Miller, director of the Center for Preventive Cardiology at the University of Maryland Medical Center in Baltimore.
That release sets off a cascade of heart-healthy biological events. Endorphins, pleasure-inducing neurotransmitters, activate receptors on the surface of the endothelium, the layer of flat cells lining blood vessels. That leads to the release of nitric oxide, which widens blood vessels—increasing blood flow, lessening inflammation, inhibiting platelet clumping, and reducing the formation of cholesterol plaque.
A 2005 study by Miller measured the blood flow of 20 volunteers before and after watching a funny movie and a sad movie. After the sad movie, blood flow was more restricted in 14 of the 20 viewers. But after the movie that made them laugh, average blood flow increased by 22 percent.
"The best laugh is one that brings tears to our eyes," says Miller, author of Heal Your Heart: The Positive Emotions Prescription to Prevent and Reverse Heart Disease, scheduled for publication by Rodale Press in September. His prescription: at least 30 minutes of exercise at least three times a week—and 15 minutes of daily laughter.
You Have to Laugh Out Loud
Funding for laughter and humor research is low—so low that when Mary Bennett, director of the Western Kentucky University School of Nursing, wanted to look into the effect of laughter on the immune system, she found herself scrounging, asking other researchers for vials and other equipment from their labs. "It's really hard to get taken seriously when you say you study laughter," she says.
But her study of 33 healthy women, published in 2003, showed that those who laughed at a humorous movie had higher levels of natural killer cell activity, which increased their ability to fight off disease. However, the effect was seen only in the subjects who laughed out loud, not in those who quietly watched the comedy.
A study in Japan that also used laboratory findings found that laughter could improve anti-inflammatory factors in the blood of people who have rheumatoid arthritis.
But the bulk of the research on laughter and health depends on subjective studies and not on evidence-based science. And some studies are contradictory. One study of 70 depressed elderly women found that laughter yoga was just as effective as exercise therapy in improving mood, as measured by self-satisfaction reports by subjects. Humor and laughter may improve muscle tone, though only when someone is laughing, and some studies do show that a good laugh can help reduce stress hormones. But other studies show that laughter doesn't affect those hormones, according to a review of the literature published by Bennett.
No doubt, a New Yorker cartoon, a good joke, or an hour spent with the Marx Brothers can feel therapeutic. But when Bennett, who has spent much of her career studying laughter and poring over the research literature, is asked whether laughter cures or prevents any disease, her quick answer is a simple "No."
Still, she adds, "I think it's a useful adjunct of real medicine. If you're going through something like chemotherapy, anything you can do to help you stay sane through something that nasty will help."